Vetenskapliga artiklar

PXL01 och förebyggande av adherenser och ärrbildning

Wiig M, Dahlin LB, Fridén J, Hagber L, Larsen SE, Mahlapuu M. (2014). PXL01 in sodium hyaluronate for improvement of hand recovery after flexor tendon repair surgery: randomized controlled trial. PLOS ONE, 9(10):e110735.
Håkansson J, Mahlapuu M, Ekström L, Olmarker K, Wiig M. (2012). Effect of Lactoferrin Peptide (PXL01) on Rabbit Digit Mobility after Flexor Tendon Repair. J. Hand Surg., 37(12):2519-25.
Wiig M, Olmarker K, Håkansson J, Ekström L, Nilsson E, Mahlapuu M. (2011).A lactoferrin-derived peptide (PXL01) for the reduction of adhesion formation in flexor tendon surgery: an experimental study in rabbits. J. Hand Surg., 36(8):656-62.
Olmarker K, Ekström L Håkansson J, Nilsson E, Wiig M, Mahlapuu M. (2010). Model for assessment of mobility of toes and healing of tendons in rabbits. J. Plast. Surg. & Hand Surg. 44(6):266-71.
Nilsson E, Björn C, Sjöstrand V, Lindgren K, Münnich M, Mattsby-Baltzer I, Ivarsson M-L, Olmarker K, Mahlapuu M. (2009).A novel polypeptide derived from human lactoferrin in sodium hyaluronate prevents post-surgical adhesion formation in the rat. Ann. Surg., 250(6):1021-8.
Shaw TJ, Martin P. (2009) Wound repair at a glance. J Cell Sci., 122(18): 3209–3213.

Grönberg A, Mahlapuu M, Ståhle M, Whately-Smith C, Rollman O. (2014).Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: A randomized, placebo-controlled clinical trial. Wound Repair & Regenerat, 22(5):613-21.
Rivas-Santiago B, Trujillo V, Montoya A, Gonzalez-Curiel I, Castaneda-Delgado J et al. (2012).Expression of antimicrobial peptides in diabetic foot ulcer. J Dermatol Sci, 65:19–26.
Ramos R, Silva JP, Rodrigues AC, Costa R, Guardao L, Schmitt F et al. (2011).Wound healing activity of the human antimicrobial peptide LL-37. Peptides, 32:1469–76.
Tokumaru S, Sayama K et al. (2005). Induction of keratinocyte migration via transactivation of the epidermal growth factor receptor by the antimicrobial peptide LL-37. J Immunol, 175(7):4662-8.
Koczulla R, von Degenfeld G, Kupatt C, Krotz F, Zahler S, Gloe T, Issbrucker K et al. (2003).An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest, 111(11):1665-72.
Scott MG, Davidson DJ, Gold MR, Bowdish D, Hancock RE. (2002). The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses. J Immunol, 169(7):3883-3891
Dorschner RA1, Pestonjamasp VK, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH,Gallo RL. (2001). Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol, 117(1):91-7.